Innovating New Treatments for People with Ultra-rare Bone Disorders and Other Diseases

A Commitment to Patients

The patients we serve are at the forefront of everything we do. We work closely with physicians, researchers and affected families in the interest of the larger patient and medical communities.

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Our Trials

We are currently enrolling patients in our Phase 3 MOVE study for palovarotene in fibrodysplasia ossificans progressiva (FOP), and we plan to initiate our first study in multiple osteochondromas (MO) in early 2018.

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Our Clinical Programs

Clementia is developing palovarotene, a retinoic acid receptor gamma (RARĪ³) selective agonist, for the treatment of people with fibrodysplasia ossificans progressiva (FOP), multiple osteochondromas (MO) and dry eye disease.

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Fibrodysplasia Ossificans Progressiva

FOP is an ultra-rare, genetic, chronic disease that causes bone growth in muscles, tendons and soft tissue and leaves most affected individuals confined to a wheelchair by the third decade of their life.

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Multiple Osteochondromas

MO, also called multiple hereditary exostoses (MHE or HME), is an ultra-rare genetic musculoskeletal condition in which multiple benign tumors, also known as osteochondromas (OCs), develop on bones.

Learn About MO